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Enzyme Activation
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Article Stearoyl coenzyme A desaturase 1 expression and activity are increased in the liver during iron overload   Pigeon, Christelle ; Legrand, Philippe ; Leroyer, Patricia ; Bouriel, Monique ; Turlin, Bruno ; Brissot, Pierre ; Loreal, Olivier
Biochimica et Biophysica Acta, 2001 , Volume 3 , n° 1535 , 275-284 p.   [ ISSN : 0006-3002 ]
Résumé :
In humans, hepatic iron overload can lead to hepatocellular carcinoma development. Iron related dysregulation of hepatic genes could play a role in this phenomenon. We previously found that the carbonyl-iron overloaded mouse was a useful model to study the mechanisms involved in the development...

ANALYSIS ; Animals ; Biosynthesis ; DESATURASE ; Disease Models,Animal ; Drug effects ; ENZYME ; Enzyme Activation ; Enzymology ; Fatty Acids ; FOIE ; FRANCE ; Gene Expression Regulation ; GENES ; GENETIQUE ; Humans ; Iron Overload ; Iron-Dextran Complex ; Liver ; MALE ; METABOLISM ; Mice ; Mice,Inbred BALB C ; Organometallic Compounds ; Research Support,Non-U.S.Gov't ; RNA ; RNA,Messenger ; Stearoyl-CoA Desaturase ; Up-Regulation
401093 : Bibliothèque générale de Rennes (Sciences animales) - Cote = Publication Biochimie
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